Flagship Product - Digital PCR

We fundamentally reduced the cost of consumables.

We can generate nanoliter-scale droplets using standard pipette tips (0.3 mm or larger), and we define this technology as Macro-Fluidic Microdroplet Technology.

0.01%

Detection sensitivity

≥95%

Valid droplets per sample

48

Max samples per run

Details
Yuanzan Digital PCR Device

Innovation

A completely different technology lineage

Macro-FDG is not an iteration of existing dPCR systems. It uses an active acoustic jetting principle built around standard-scale tips.

DimensionMacro-FDGMicrofluidicMicro-well
Channel / nozzleStandard tips (0.3-0.6 mm)Micro-channels (<0.1 mm)Micro-wells (pL)
Droplet generationActive acoustic jetting + recoilOil shear at junctionPassive partitioning
Sample throughput48/run8-24/run16/run
Consumable cost/run~$0.50~$10-20~$15-30
ScalabilityLinear scaling, simple manufacturingComplex micro-fabricationFixed chip design

Innovation

dPCR for Everyone

Digital PCR has long been powerful but expensive, locked into proprietary consumables, and limited to low-throughput use. Yuanzan changes this with a completely different technology lineage.

When consumable cost drops by 20-40x per sample, the economic barrier to absolute quantification disappears.

With 48-sample throughput and walk-away automation, dPCR becomes a practical daily lab tool.

The workflow avoids proprietary chips, locked reagents, and forced service contracts.

Millimeter-scale channels are physically resistant to clogging with challenging clinical samples.

We are open

Our qPCR is open at every layer

Most qPCR systems on the market are closed off — proprietary consumables, bundled computers, closed algorithms. We take the opposite approach: open at every layer, so your lab keeps control of cost, workflow, and data.

Consumable Freedom

Compatible with any brand of 0.1/0.2 mL tubes, 8-strip tubes, and 96-well plates. No proprietary plastics. No premium consumables.

No Bundled Computer

Built-in 9″ touch screen and embedded computer. No separate PC needed. VQ-200 offers USB/RS485 for custom integration.

Open Analysis Algorithm

Not a black box. Acquisition parameters and algorithms can be customized for specific reagent kits. Custom reports. LIMS integration.

Automation Ready

Motorized lid, auto-loading chamber, USB/RS485. Ready for robotic integration and dark-lab environments.

Technology

We use standard-scale nozzles to generate nanoliter droplets

Our digital PCR platform generates nanoliter droplets through a macro-fluidic nozzle rather than complex microfluidic chips. A piezoelectric stack produces precise displacement, transfers it through drive oil as an acoustic pressure wave, and creates a controlled micro-jet at the nozzle tip for stable droplet formation.

105 μm

Uniform droplet diameter

0.6 nL

Approximate droplet volume

PID

Closed-loop motion control

Macro-FDG droplet generation nozzle forming digital PCR microdroplets

Droplet size:105μm(0.6 nL)

Technology

Core Features of Digital PCR

Uniform digital PCR droplet array micrograph with Macro-FDG physical principles

01

Acoustic coupling

Near-rigid pressure-wave transmission moves through the drive oil with microsecond-scale delay, giving the nozzle a fast and repeatable actuation signal.

02

Active recoil

A reverse acoustic wave sharpens droplet break-off and suppresses satellite droplets, improving the consistency of each partition.

03

Variable impedance compensation

Adaptive frequency and voltage control keep the jetting state stable as the fluid load changes during droplet generation.

04

Weber number control

Waveform shaping controls dV/dt so droplet size remains stable and less dependent on small variations in tip geometry.

Equipment Has Wide Applications

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